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gmuF [2018-06-22 18:35:02]
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gmuF [2018-06-22 18:35:02]

mannose-6-P-isomerase
Locus
BSU05870
Isoelectric point
5.89
Molecular weight
35.34 kDa
Protein length
315 aa Sequence Blast
Gene length
945 bp Sequence Blast
Function
glucomannan utilization
Product
mannose-6-P-isomerase
Essential
no
Synonyms
ydhS
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of glucomannan

    • Gene

    Coordinates
    631,808 → 632,755

    The protein

    Paralogous protein(s)

  • Pmi, ManA

    • Structure

  • 1QWR (ManA, 58% identity)

    • Expression and Regulation

    Operons

    Genes
    gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • GmuR: repression, PubMed, in GmuR regulon
  • CcpA: repression, PubMed, in CcpA regulon
  • AbrB: activation, PubMed, in AbrB regulon

    • Regulation

  • induced by cellobiose (GmuR) PubMed
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    Biological materials

    Mutant

  • MGNA-C194 (ydhS::erm), available at the NBRP B. subtilis, Japan
  • BKE05870 (ΔgmuF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AGGCTCTAAAAATAATGGAT, downstream forward: _UP4_CCTTAATGAATGGGGGAGTT
  • BKK05870 (ΔgmuF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AGGCTCTAAAAATAATGGAT, downstream forward: _UP4_CCTTAATGAATGGGGGAGTT

    • References

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